How Humans Made Malaria So Deadly

Thanks to http://www.givewell.org/ for sponsoring this video! To learn more about the Against Malaria Foundation, visit: http://www.givewell.org/AMF or https://www.againstmalaria.com.

Thanks also to our supporters on https://www.patreon.com/MinuteEarth
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FYI: We try to leave jargon out of our videos, but if you want to learn more about this topic, here are some keywords to get your googling started:

Malaria – a life-threatening disease caused by parasites that are transmitted to people through the bites of infected female Anopheles mosquitoes.
Parasite – an organism that benefits by living in/on a host organism and deriving nutrients at the host’s expense.
Host – an organism in/on which another organism lives.
Protozoa – a group of single-celled microscopic animals (not bacteria or viruses) that includes the Plasmodium species.
Plasmodium – a genus of parasitic protozoa, many of which cause malaria in their hosts. Four species regularly infect humans: P. falciparum, P. vivax, P. malariae, & P. ovale.
P. falciparum – the Plasmodium species that kills the most people, by causing malignant malaria, the most dangerous form of malaria.
Anopheles gambiae – a ‘complex’ of at least seven species of mosquitoes that are the main vectors of P. falciparum in sub-Saharan Africa.
Species complex – a group of closely related species that look so similar that the boundaries between them are often unclear.
Hunting and gathering – depending primarily on wild foods for subsistence
Paleontology – the study of fossils and what fossils tell us about the past, about evolution, and about how humans fit into the world.
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Credits (and Twitter handles):
Script Writer: Alex Reich (@alexhreich)
Script Editor: Emily Elert (@eelert)
Video Illustrator: Qingyang Chen
Video Director: Emily Elert (@eelert)
Video Narrator: Kate Yoshida (@KateYoshida)
With Contributions From: Henry Reich, Ever Salazar, Peter Reich, David Goldenberg
Music by: Nathaniel Schroeder: http://www.soundcloud.com/drschroeder

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If you liked this week’s video, we think you might also like:

Amazing animation of seasonal temperature suitability for malaria https://goo.gl/63pYGt
Americapox CGPGrey video https://www.youtube.com/watch?v=JEYh5WACqEk
The History of Malaria, an Ancient Disease http://www.cdc.gov/malaria/about/history/

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References:

Carter, R., & Mendis, K. N. (2002). Evolutionary and historical aspects of the burden of malaria. Clinical microbiology reviews, 15(4), 564-594. http://cmr.asm.org/content/15/4/564.full

Gething, P. W., et al. (2011). A new world malaria map: Plasmodium falciparum endemicity in 2010. Malaria journal, 10(1), 1. http://malariajournal.biomedcentral.com/articles/10.1186/1475-2875-10-378

Gething, P. W., et al. (2011). Modelling the global constraints of temperature on transmission of Plasmodium falciparum and P. vivax. Parasites & Vectors, 4(1), 1. http://parasitesandvectors.biomedcentral.com/articles/10.1186/1756-3305-4-92

Hay, S. I., et al. (2004). The global distribution and population at risk of malaria: past, present, and future. The Lancet infectious diseases, 4(6), 327-336. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145123/

Institute for Health Metrics and Evaluation (IHME). (2016). GBD Compare Data Visualization. Seattle, WA: IHME, University of Washington. Retrieved from http://vizhub.healthdata.org/gbd-compare.

Liu, W., et al. (2010). Origin of the human malaria parasite Plasmodium falciparum in gorillas. Nature, 467(7314), 420-425. doi: 10.1038/nature09442

Malaria: Fact sheet (April 2016). Retrieved from http://www.who.int/mediacentre/factsheets/fs094/en/

Packard, R. M. (2007). The making of a tropical disease: a short history of malaria (pp. 1-66 ). Baltimore.

Rich, S. M., et al. (2009). The origin of malignant malaria. Proceedings of the National Academy of Sciences, 106(35), 14902-14907. doi: 10.1073/pnas.0907740106

Shah, S. (2010). The Fever: how malaria has ruled humankind for 500,000 years (pp. 1-33). Macmillan.

Sundararaman, S. A., et al. (2016). Genomes of cryptic chimpanzee Plasmodium species reveal key evolutionary events leading to human malaria. Nature communications, 7. DOI: 10.1038/ncomms11078

Webb, J. L. (2009). Humanity’s burden: a global history of malaria (pp. 1-91). Cambridge: Cambridge University Press.

World Health Organization. (2015). World malaria report 2015. World Health Organization. Retrieved from http://www.who.int/malaria/publications/world-malaria-report-2015/report/en/

MinuteEarth: The Story of Our Planet

Our first video ever! Agriculture, hula hoops, SARS, and THIS video: how long did they take to get around the earth?

CREDITS
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Created by Henry Reich, with Alex Reich, Peter Reich, Rose Eveleth, Emily Elert, and John Guittar.
Music by Nathaniel Schroeder http://www.soundcloud.com/drschroeder
Thanks to ScienceAlert for support – http://www.sciencealert.com

MinuteEarth is produced by Neptune Studios LLC
https://neptunestudios.info

SUPPORT MINUTEEARTH
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If you like what we do, you can help us!:
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The Real Animals of Madagascar | Animal Science for Kids

Jessi and Squeaks introduce you to the amazing, unusual animals and plants from a place like nowhere else on earth: Madagascar!
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Like SciShow? Want to help support us, and also get things to put on your walls, cover your torso and hold your liquids? Check out our awesome products over at DFTBA Records: http://dftba.com/SciShow

Or help support us by becoming our patron on Patreon:
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SOURCES:
http://www.pbs.org/edens/madagascar/eden.htm

http://evolution.berkeley.edu/evolibrary/news/091001_madagascar

http://animals.sandiegozoo.org/animals/fossa

http://voices.nationalgeographic.com/2015/04/13/lemurs-of-madagascar/

http://www.pnas.org/content/104/34/13723.full

http://www.wildmadagascar.org/kids/

What to know about the Ebola outbreak

Emergency room physician and ABC News medical correspondent Dr. Darien Sutton answers questions about the outbreak as Ebola-related searches spike online.

READ more from ABC News:
‘We’re working on it’: HHS Secretary Robert F. Kennedy Jr. on Ebola, hantavirus response:
https://tinyurl.com/2vrc7s8x

SUBSCRIBE to GMA: https://youtube.com/@GMA?si=ka34lqdEy8NRwJtT

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To read the full story and others, visit http://www.goodmorningamerica.com

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Watch full episodes of GMA: https://abcnews.link/8SAXtIX
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From Drugs to Jesus, Machine Gun Preacher’s Wife Tells Her Story

Before she was the “Machine Gun Preacher’s wife”, Lynn lived a life full of stripping, drugs and partying until she found herself facing prison time. She decided to make a deal with God and her life was never the same

Earth Day! A Marvel Super Heroes: What The–?! Special

Get ready for Earth Day 2011 on Friday, April 22 with a special Marvel Super Heroes: What The–?! promo for the all-new Disneynature motion picture release “African Cats” opening on Earth Day!

M.O.D.O.K.’s on safari in the African savanna and, per usual, his unbridled thoughtlessness can’t go unnoticed. Watch what happens when The Incredible Hulk, Black Panther and Zabu team up to teach the big-headed blowhard an Earth Day lesson he won’t soon forget!

Be sure to see “African Cats” during its opening week (April 22-28) and YOU can help “Save the savanna.” For details, check out: http://disney.go.com/disneynature/africancats/ About Marvel Super Heroes: What The–?
Witness a Marvel Universe like you have never seen before with a comedic take on your favorite heroes and villains using stop motion animation! Marvel Super Heroes: What The–?! continues Marvel’s tradition of comic book satires as made popular in the Marvel comic book series NOT BRAND ECHH (from the 1960s) and What The–?! (from the 1990s). This time around, it’s not only a new millennium but a new medium, with Marvel exercising its might in the world of stop-motion animation.

About Marvel Entertainment
Marvel Entertainment, LLC, a wholly-owned subsidiary of The Walt Disney Company, is one of the world’s most prominent character-based entertainment companies, built on a proven library of over 10,000 characters featured in a variety of media over seventy years. Marvel utilizes its character franchises in entertainment, licensing and publishing.